NANDROLONE DECANOATE is a steroid and is indicated for the management of the anemia of renal insufficiency and has been shown to increase hemoglobin and red cell mass.
The kidneys normally produce the hormone erythropoietin, which stimulates the production of red blood cells in the bone marrow. People with chronic kidney disease often experience anemia, or a low red blood cell count, caused by inadequate production of erythropoietin. Therapy with Nandrolone Decanoate may help alleviate this condition, known as anemia of renal insufficiency.
Nandrolone Decanoate may stimulate the production of erythropoietin, leading to increased red blood cell production, explains the National Cancer Institute. In an October 2005 article published in the "European Journal of Clinical Investigation," Drs. Robert Deicher and Walter Hörl report that use of nandrolone decanoate proves beneficial for some male patients with anemia of renal insufficiency. The authors, however, advise against using the drug for female patients due to side effects. Among female patients, Nandrolone Decanoate may cause masculinizing side effects, such as increased body hair, disruption of the menstrual cycle, deepening of the voice and male-pattern hair loss.
Nandrolone decanoate may cause serious side effects in the liver. The FDA-approved prescribing information warns that a condition known as peliosis hepatis may develop with use of nandrolone decanoate. Blood-filled cysts develop throughout the liver with peliosis hepatis. The cysts may rupture, causing severe and potentially life-threatening internal bleeding, reports "The Merck Manual for Healthcare Professionals." Although uncommon, patients with peliosis hepatis may develop liver failure.